Monkeying about with Medicine

This is from Thursday’s i paper which is producing some very interesting pieces on science:

Despite our advances in technology and medicine we seem to be fighting a never-ending battle against diseases and ailments. As viruses become more complex an bacteria become resistant to antibiotics, it seems the lab-made drugs awe have become so dependent on may no longer provide the cures we need. Perhaps this is why we are now turning to nature in the hope that there may be a remedy tucked away somewhere in a remote tropical rainforest.

It could be that our closest living relatives, non-human primates, hold some of the answers. Many species, including chimpanzees, make use of the natural resources in their habitats to self-medicate and improve their health. This behaviour, known as zoopharmocognosy, typically involves ingestion or topical application of plants, soils,insects or even psychoactive drugs in order to treat and prevent diseases.

One of the most well known examples are domestic dogs and cats eating grass in order to induce vomiting if they have an upset stomach of internal parasite.

Most studies or animal self-medication are in non-human primates. One of the fist documented cases was in 1983, when researchers observed chimpanzees in Tanzania folding and swallowing Aspilia species leaves without chewing them. Other scientists noted the same behaviour in chimp colonies in Uganda and Nigeria.

This is quite unusual, not only because there is no nutritional benefit in swallowing these laves whole, but also because the leaves themselves have a rough and bristly surface.

t was only as recently as 1996 that the scientists suggested was a form of self medication, as research began t link it with faeces full of undigested leaves and expelled parasitic worms. It seemed the chimpanzees were swallowing the leaves to take advantage of their rough and bristly surface to hook onto the worms as they passed through their digestive system, pruning their intestines…

The tamarin monkeys of South America. however, have found a different method to remove internal parasites. They are able to swallow large seeds of up to 1.5cm, which then pass through their digestive tract dislodging or expelling internal parasites.

Another odd behaviour that is also thought of as a kind of self-medication is soil and clay consumption, which has been observed in a number of columbine monkeys. It was generally believed that soil is even as an additional source of minerals or to absorb and neutralise certain plant compounds, which might be toxic of interfere with digestion. Although there is no compelling evidence that soil consumption detoxifies chemicals, event studies have found that some clays have antibacterial properties.

Charcoal consumption on the other hand, is known to relieve indigestion and, more importantly, can be used as an antidote to poisons. This method of self-medication is still widely used among humans, but has only been reported in one species f primate, the Zanzibar red colobus monkey. The diet of these monkeys mainly consists of young leaves that are fairly toxic, and by ingesting charcoal they are able to neutralise the effects.

Anointing behaviour, for fur-rubbing, is where animals rub strongly smelling substances into their fur. There are a few explanations for this … including social singling and sexual see tin, but it can also be a form of self medication against skin parasites.

Fur-Ruing has been recorded in a wide range of primate species. Black lemurs, for instance, use toxic millipede to rub their fur, whereas black-handed spider monkeys use aromatic leaves, orangutang use Commelina herbs and owl monkeys, plants and millipedes.

Tufted capuchin monkeys anoint with a surprisingly wide range of materials – including plants, aromatic leaves, onions, virus fruits and invertebrates such as ants and millipedes. All of these items have some form of insect repelling properties. Monkeys typically apply than more frequently during the rainy season when there’re more flying insects around.

The different forms of self-medicating by our cousins provide simple and natural solutions to combat parasites and other ailments. The research could also prove useful insights for the future of pharmacology. One of the founders of zoopharmagognosy, Eloy Rodriguez, at Cornell University, has argued that some of the compounds animals use to kill parasite worms may be useful against tumours.

Many plant species have been found to be rich in a substances which have antimicrobial properties. Despite this, a study suggests less than 5% of tropical first plant have been screened for their medicinal properties. Pharmaceutical firms and medical institutes have been screening rainforest plant for anti-cancer and anti-HIV compounds with some success.

This research holds the promise of endless possibilities and, by looking at the specific items used by primates and other organisms of self-medication, we can then identify whether their chemical compositions would be suitable for curing or aiding the treatment of human diseases and illnesses.

Or we could instead fund more research by herbalists to work on more natural remedies that would likely be safer and have fewer side effects, but that would take profits away from Big Pharma.

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